In higher education (HE), some of the distinctions between conventional, campus-based universities and those dedicated to distance education are being eroded through the use of information and communication technology. Despite huge investments in technology to enhance teaching and learning, there has been a considerable lack of clarity about what this actually signifies in practice. Implementation decisions are frequently technology-led rather than being focused on clearly defined educational goals. This article attempts to examine key issues and synthesise a number of important debates relating to teaching and learning with technology in HE. It examines some of the key factors influencing how technology is utilised in HE teaching and learning. It argues that decision-making by managers and teachers with regard to technology use needs to be founded upon evidence that takes account of all of those factors, not just a narrow selection of them. Rather than just considering technical issues and/or the idealised promises made about technologies, "joined-up thinking" is required to integrate the multiple contextual factors that all influence how technology is actually used in teaching and learning.