Relevance is discussed in light of 21st c. communication skills and relevance. How do these areas impact both the face-to-face and online candidates in the MAT and MAED programs to positively impact P-12 students? Relevance theory and communication in 21st c. is clarified for working in both face-to-face and online learning environments leading current and future teachers into needed skills for education and specifically literacy. The authors offer their insights including anecdotal evidence from current successful practices.