This article provides a description and review of the "Comprehensive Executive Function Inventory" (CEFI; Naglieri & Goldstein, 2013), published by Multi-Health Systems Inc. (MHS). It is a rating scale developed to measure a wide array of Executive Function (EF) abilities in individuals aged 5 through 18 years. Completed by a parent, teacher, and/or child/youth (12-18 years of age only), the CEFI is designed to provide normative information on an individual's EF abilities, including strengths and weaknesses related to the domains evaluated. Suitable for assessment, diagnostic, or intervention/treatment processes, the CEFI is relevant in clinical, educational, and research contexts. The CEFI can be administered and interpreted by psychologists and professionals from related fields who have MHS "B-level" qualifications, and who are familiar with educational and psychological testing standards. The development of the CEFI was grounded in current theoretical and research literature as well as the authors' clinical and research experience. EF is conceptualized as representing higher order cognitive processes, such as decision making, planning, problem solving, mental flexibility, and inhibition. These processes are primarily performed by the pre-frontal areas of the frontal lobe, and play a role in cognition, behaviour, and emotion. According to the authors, EF is best measured by observation in real-life situations or by assessing cognitive processes. The CEFI includes a Technical Manual and three separate forms for each respondent. The manual provides best practices for administration and interpretation. All forms are available in English and Spanish in the MHS QuikScore format, and can be administered via paper or online. Overall, this review reveals that the CEFI is apparently a strong measure of EF with relevance for a number of settings. Psychologists working in schools may find it particularly useful when exploring the cognitive abilities of children with disabilities known to arise from EF impairments (i.e., ADHD, ASD, LD).