ERIC Number: EJ1050808
Record Type: Journal
Publication Date: 2015-Feb
Abstractor: As Provided
Reference Count: 57
Cardiac Reactivity and Stimulant Use in Adolescents with Autism Spectrum Disorders with Comorbid ADHD Versus ADHD
Bink, M.; Popma, A.; Bongers, I. L.; van Boxtel, G. J. M.; Denissen, A.; van Nieuwenhuizen, Ch.
Journal of Autism and Developmental Disorders, v45 n2 p481-494 Feb 2015
A large number of youngsters with autism spectrum disorders (ASD) display comorbid attention deficit/hyperactivity disorder (ADHD) symptoms. However, previous studies are not conclusive whether psychophysiological correlates, like cardiac reactivity, are different for ASD with comorbid ADHD (ASD+) compared to ADHD. Therefore, the current study investigated (dis)similarities in cardiac reactivity and attention task performance. In a clinical sample, adolescents diagnosed with ASD+ (n = 20) versus ADHD (n = 36) and stimulant medication use (56%) were compared during a baseline with eyes closed and task performance. Results for cardiac reactivity were similar for both diagnostic groups. Stimulant-medicated adolescents showed decreased adaptation of LF/HF ratio and faster reaction times than stimulant-free adolescents. The current study underlines the psychophysiological overlap of ADHD symptoms in adolescents with ASD+ and adolescents with ADHD.
Descriptors: Attention Deficit Hyperactivity Disorder, Autism, Pervasive Developmental Disorders, Adolescents, Stimulants, Drug Use, Drug Therapy, Correlation, Comorbidity, Metabolism
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Publication Type: Journal Articles; Reports - Research
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