ERIC Number: EJ1050803
Record Type: Journal
Publication Date: 2015-Feb
Abstractor: As Provided
Reference Count: 44
Alpha Asymmetry in Infants at Risk for Autism Spectrum Disorders
Gabard-Durnam, Laurel; Tierney, Adrienne L.; Vogel-Farley, Vanessa; Tager-Flusberg, Helen; Nelson, Charles A.
Journal of Autism and Developmental Disorders, v45 n2 p473-480 Feb 2015
An emerging focus of research on autism spectrum disorder (ASD) targets the identification of early-developing ASD endophenotypes using infant siblings of affected children. One potential neural endophenotype is resting frontal electroencephalogram (EEG) alpha asymmetry, a metric of hemispheric organization. Here, we examined the development of frontal EEG alpha asymmetry in ASD high-risk and low-risk infant populations. Our findings demonstrate that low and high-risk infants show different patterns of alpha asymmetry at 6 months of age and opposite growth trajectories in asymmetry over the following 12 months. These results support the candidacy of alpha asymmetry as an early neural ASD endophenotype.
Descriptors: Pervasive Developmental Disorders, Autism, Infants, At Risk Persons, Brain Hemisphere Functions, Neuropsychology, Early Intervention, Disability Identification, Siblings, Child Development
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Authoring Institution: N/A