ERIC Number: EJ1050711
Record Type: Journal
Publication Date: 2015-Jan
Abstractor: As Provided
Reference Count: 26
Spectroscopic Determination of Triclosan Concentration in a Series of Antibacterial Soaps: A First-Year Undergraduate Laboratory Experiment
Wyllie, Graeme R. A.
Journal of Chemical Education, v92 n1 p153-156 Jan 2015
The antibacterial chemical triclosan is a common component in personal care products but recently the subject of many reports concerning environmental toxicity and health impacts. Although triclosan concentration in a soap can be determined simply via high-performance liquid chromatography, this is a technique not routinely available in the general chemistry laboratory. Here we report an experiment, suitable for the first-year undergraduate laboratory, to determine the percentage of triclosan in a series of antibacterial soaps using UV-vis spectroscopy following conversion of the triclosan to an azo-dye through reaction with nitrite and 4-sulfanilic acid. Additional experiments that build on this and look at either triclosan removal from solution or the impact of triclosan on a biological system are also discussed. Although designed for first-year undergraduate students, this laboratory is also adaptable to science outreach programs.
Descriptors: Spectroscopy, Laboratory Experiments, Undergraduate Students, Chemistry, Drug Education, Hands on Science, Scientific Methodology, Laboratory Safety, Science Education, Teaching Methods
Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: firstname.lastname@example.org; Web site: http://pubs.acs.org/jchemeduc
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education; Postsecondary Education
Authoring Institution: N/A
Identifiers - Location: Minnesota