Pragmatic functioning of autism spectrum disorder (ASD) children is rarely examined in socially-meaningful contexts. This study investigates the way oppositional episodes are handled in such contexts by 25 families, 10 with ASD and 15 with typically-developing children. Oppositions occur whenever someone protests, refuses or denies someone else's action, request or statement. The analysis focuses on justifications accounting for the opposition and on their immediate persuasive effect. Analyses of 1,065 oppositional episodes show no differences in justifications among partners and children, except for ASD children with a verbal age 3-4 years, who justify less than their matched controls. The persuasive effect of justifications on children and on partners differs according to their group and verbal age. Implications of the study and future perspectives are discussed.