When used consistently and correctly every time, condoms can prevent against the spread of sexually transmitted infections (STIs) and unplanned pregnancies. Condoms are a significant prevention method viable for all populations. This study was conducted among students (277) at a Midwestern University who were enrolled in a personal health and wellness course and examined their reported use of condoms and reported barriers. Results indicated that almost knowledge alone was not enough for consistent condom use. Only 34.29% of students who reported having sex in the past 30 days, reported using a condom always. The most frequently reported answer for not using a condom was trust in partner's monogamy. In addition, the findings also indicate that male students who reported having been taught to put on a condom by a friend were more likely to use a condom. The study results support the theory that knowledge alone is not enough for consistent condom use among college students.