With the "flattening" of the global economy in the 21st century, the teaching of Science, Technology, Engineering, and Mathematics (STEM) has taken on new importance as economic competition has become truly global. STEM education has evolved into a meta-discipline, an integrated effort that removes the traditional barriers between these subjects, and instead focuses on innovation and the applied process of designing solutions to complex contextual problems using current tools and technologies. Engaging students in high quality STEM education requires programs to include rigorous curriculum, instruction, and assessment, integrate technology and engineering into the science and mathematics curriculum, and also promote scientific inquiry and the engineering design process. All students must be a part of the STEM vision, and all teachers must be provided with the proper professional development opportunities preparing them to guide all their students toward acquiring STEM literacy. By focusing on student engagement, educators from institutions of higher education and K-12 schools can work together to develop pedagogical models that provide rigorous, well-rounded education and outstanding STEM instruction. This paper defines the necessary attributes of STEM programs designed to engage all students, describes a number of model programs focused on student engagement, and discusses assessments in progress.