ERIC Number: EJ1044305
Record Type: Journal
Publication Date: 2013-Oct
Abstractor: As Provided
Reference Count: 19
Illuminating the Black Box of Genome Sequence Assembly: A Free Online Tool to Introduce Students to Bioinformatics
Taylor, D. Leland; Campbell, A. Malcolm; Heyer, Laurie J.
American Biology Teacher, v75 n8 p572-577 Oct 2013
Next-generation sequencing technologies have greatly reduced the cost of sequencing genomes. With the current sequencing technology, a genome is broken into fragments and sequenced, producing millions of "reads." A computer algorithm pieces these reads together in the genome assembly process. PHAST is a set of online modules (http://gcat.davidson.edu/phast) designed to teach advanced high school and college students the genome assembly process. PHAST allows users to assemble phage genomes in real time and includes tutorials detailing the complexities of genome assembly. With PHAST, students learn concepts behind genome assembly and understand how mathematics solves biological problems such as genome assembly.
Descriptors: Biology, Information Science, Genetics, Educational Technology, High School Students, Secondary School Science, College Students, College Science, Scientific Concepts, Concept Formation, Teaching Methods, Internet, Computer Uses in Education
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Publication Type: Journal Articles; Reports - Research
Education Level: High Schools; Secondary Education; Higher Education; Postsecondary Education
Authoring Institution: N/A