ERIC Number: EJ1042873
Record Type: Journal
Publication Date: 2014-Nov
Abstractor: As Provided
Reference Count: 117
Rates and Predictors of Adherence to Psychotropic Medications in Children with Autism Spectrum Disorders
Logan, Sarah L.; Carpenter, Laura; Leslie, R. Scott; Hunt, Kelly S.; Garrett-Mayer, Elizabeth; Charles, Jane; Nicholas, Joyce S.
Journal of Autism and Developmental Disorders, v44 n11 p2931-2948 Nov 2014
Medication adherence in children is poor, particularly among those with chronic or mental health disorders. However, adherence has not been fully assessed in autism spectrum disorders (ASDs). The validated proportion of days covered method was used to quantify adherence to psychotropic medication in Medicaid-eligible children who met diagnostic criteria for ASD between 2000 and 2008 (N = 628). Among children prescribed attention deficit hyperactivity disorder (ADHD) medications, antidepressants, or antipsychotics, 44, 40 and 52 % were adherent respectively. Aggressive behaviors and abnormalities in eating, drinking, and/or sleeping, co-occurring ADHD, and the Medication Regimen Complexity Index were the most significant predictors of adherence rather than demographics or core deficits of ASD. Identifying barriers to adherence in ASD may ultimately lead to improved treatment outcomes.
Descriptors: Autism, Pervasive Developmental Disorders, Drug Therapy, Compliance (Psychology), Attention Deficit Hyperactivity Disorder, Aggression, Behavior Disorders, Eating Habits, Sleep, Comorbidity, Predictor Variables, Barriers, Children
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Authoring Institution: N/A