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ERIC Number: EJ1041506
Record Type: Journal
Publication Date: 2014-Sep
Pages: 8
Abstractor: As Provided
Reference Count: N/A
ISSN: ISSN-1072-0502
A Unifying Model of the Role of the Infralimbic Cortex in Extinction and Habits
Barker, Jacqueline M.; Taylor, Jane R.; Chandler, L. Judson
Learning & Memory, v21 n9 p441-448 Sep 2014
The infralimbic prefrontal cortex (IL) has been shown to be critical for the regulation of flexible behavior, but its precise function remains unclear. This region has been shown to be critical for the acquisition, consolidation, and expression of extinction learning, leading many to hypothesize that IL suppresses behavior as part of a "stop" network. However, this framework is at odds with IL function in habitual behavior in which the IL has been shown to be required for the expression and acquisition of ongoing habitual behavior. Here, we will review the current state of knowledge of IL anatomy and function in behavioral flexibility and provide a testable framework for a single IL mechanism underlying its function in both extinction and habit learning.
Cold Spring Harbor Laboratory Press. 500 Sunnyside Boulevard, Woodbury, NY 11797-2924. Tel: 800-843-4388; Tel: 516-367-8800; Fax: 516-422-4097; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Evaluative
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A