The purpose of this study is to examine the effect of metacognition on one's academic locus of control. The study's sample group consists of 451 university students enrolled in various programs at Sakarya University, Turkey. In this study, the Metacognitive Awareness Inventory and the Academic Locus of Control Scale were used. The correlations and path analysis were examined. The hypothesis model was tested through path analysis. The findings of the path analysis reveal that while an internal academic locus of control was predicted to have a positive relation with metacognition, an external academic locus of control was predicted to have a negative relation. In conclusion, the research indicates that metacognition affects academic locus of control in that students whose internal academic locus of control is high are more likely to adopt metacognition than are students whose external academic locus of control is high. Therefore, the current findings act to increase our understanding of the different relationships between metacognition and academic locus of control.