ERIC Number: EJ1038288
Record Type: Journal
Publication Date: 2014-Jan
Abstractor: As Provided
Reference Count: 29
Use of Dysmorphology for Subgroup Classification on Autism Spectrum Disorder in Chinese Children
Wong, Virginia C. N.; Fung, Cecilia K. Y.; Wong, Polly T. Y.
Journal of Autism and Developmental Disorders, v44 n1 p9-18 Jan 2014
Data from 1,261 Chinese Autistic Spectrum Disorder (ASD) patients were evaluated and categorized into dysmorphic (10.79%) and non-dysmorphic groups (89.21%) upon physical examination by the presence of dysmorphic features. Abnormal MRI/CT result, IQ scores and epilepsy were significantly associated with the dysmorphic group of ASD children. However, gender, EEG abnormality and family history and recurrence of ASD were not found to be significantly different between group statuses. It is suggested that results collected from the Chinese population generally resembles that found in the Caucasians with ethnical differences still present. Current study supports the result shown in Miles' study (Miles et al. in "Am J Med Genet" 135A:171-180, 2005), in which heterogeneity subtypes of autism of different genetic origins which could be distinguished by presence of dysmorphic features on the patients.
Descriptors: Foreign Countries, Pervasive Developmental Disorders, Autism, Classification, Intelligence Quotient, Epilepsy, Correlation, Comparative Analysis, Gender Differences, Racial Differences, Ethnicity, Congenital Impairments, Diagnostic Tests, Visual Aids, Medicine, Genealogy, Patients
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Authoring Institution: N/A
Identifiers - Location: China