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ERIC Number: EJ1037829
Record Type: Journal
Publication Date: 2013-Jul
Pages: 9
Abstractor: As Provided
Reference Count: 27
ISBN: N/A
ISSN: ISSN-0162-3257
The Broader Autism Phenotype in Simplex and Multiplex Families
Gerdts, Jennifer A.; Bernier, Raphael; Dawson, Geraldine; Estes, Annette
Journal of Autism and Developmental Disorders, v43 n7 p1597-1605 Jul 2013
Mothers, fathers, and siblings from 87 multiplex (M-mothers, M-fathers, and M-siblings) and 41 simplex (S-mothers, S-fathers, and S-siblings) Autism spectrum disorder families were assessed using the Broader Phenotype Autism Symptom Scale. S-mothers, S-fathers, and S-siblings showed more social interest and were more expressive in their use of nonverbal communication compared to M-mothers, M-fathers, and M-siblings. Conversational skills were also improved in S-fathers and S-siblings compared to M-fathers and M-siblings. S-siblings showed significantly lower rigidity and intense interests compared to M-siblings. The decreased number and intensity of broader autism phenotype traits observed in parents and siblings within simplex families provide behavioral evidence consistent with findings of increased de novo genetic events in simplex families.
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A