In this study, an e-learning environment was designed for teacher candidates. Teacher candidates developed multimedia-based projects by means of multimedia tools. This research aims to determine the effects of online and blended learning approaches on the success level of multimedia projects and the teacher candidates' attitudes, opinions and perceptions on e-learning. This study used a combination of qualitative and quantitative methods. There were two different groups in the study: online and blended groups. The online and the blended groups consisted of 30 and 32 teacher candidates, respectively. Teacher candidates in the blended group developed multimedia-based projects and shared information communicating in a WiziQ and Facebook environment with their peers and instructors when they were not at school. On the other hand, the teacher candidates in the online group communicated with their instructors and peers only in a WiziQ and Facebook environment. The results showed that the blended learning approach was more effective than the online learning approach. The usability of online learning and blended learning in higher education is addressed in recommendations for future research and practice.