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ERIC Number: EJ1032470
Record Type: Journal
Publication Date: 2014-Jun
Pages: 6
Abstractor: As Provided
Reference Count: 17
ISSN: ISSN-0021-9584
A Comprehensive Microfluidics Device Construction and Characterization Module for the Advanced Undergraduate Analytical Chemistry Laboratory
Piunno, Paul A. E.; Zetina, Adrian; Chu, Norman; Tavares, Anthony J.; Noor, M. Omair; Petryayeva, Eleonora; Uddayasankar, Uvaraj; Veglio, Andrew
Journal of Chemical Education, v91 n6 p902-907 Jun 2014
An advanced analytical chemistry undergraduate laboratory module on microfluidics that spans 4 weeks (4 h per week) is presented. The laboratory module focuses on comprehensive experiential learning of microfluidic device fabrication and the core characteristics of microfluidic devices as they pertain to fluid flow and the manipulation of samples. Experiments include the cleanroom-free fabrication of glass-polydimethylsiloxane (PDMS) microfluidic devices by use of thermoplastic molds and soft lithography, determination of the zeta potential at the microchannel walls, investigations of electroosmotic flow, determination of Péclet numbers, and diffusion coefficients based on diffusion-limited reagent mixing. The module concludes with the development of a microchannel electrophoresis lab-on-a-chip device with in-line fluorimetric detection for the separation of a DNA ladder. This laboratory module has been offered for two consecutive years and has received favorable student feedback.
Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education; Postsecondary Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A