ERIC Number: EJ1028485
Record Type: Journal
Publication Date: 2013-Oct
Abstractor: As Provided
Reference Count: N/A
Medical Mycology and the Chemistry Classroom: Germinating Student Interest in Organic Chemistry
Bliss, Joseph M.; Reid, Christopher W.
Journal of Chemical Education, v90 n10 p1320-1324 Oct 2013
Efforts to provide active research context to introductory courses in basic sciences are likely to better engage learners and provide a framework for relevant concepts. A simple teaching and learning experiment was conducted to use concepts in organic chemistry to solve problems in the life sciences. Bryant University is a liberal arts university with new programs in biological and environmental sciences. This laboratory exercise was developed for introductory organic chemistry and designed to highlight its applicability to the biological sciences. Students participated in an ongoing project to identify antigens on the surface of "Candida albicans" hyphae by testing a variety of lipid extraction procedures and characterizing the fatty acid and carbohydrate composition of their extractions by thin-layer chromatography and gas chromatography-mass spectrometry. Student extracts were also tested in an immunoblot assay with a specific antibody fragment (scFv) that recognizes an unknown component of the cell surface of "C. albicans" hyphae. In order to build communication skills, students were required to prepare and present posters detailing the project and their findings.
Descriptors: Science Instruction, Science Experiments, Organic Chemistry, College Science, Science Laboratories, Biological Sciences, Scientific Concepts, Spectroscopy, Undergraduate Study
Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: firstname.lastname@example.org; Web site: http://pubs.acs.org/jchemeduc
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education; Postsecondary Education
Authoring Institution: N/A