Collaboration dispositions keep attracting high attention in the business world for organizational competition and teamwork efficiency. Educators also highly value the cultivation of youngsters' thinking strategies and styles which facilitate their learning performance and even career achievement. This study was conducted to identify the relationship among thinking styles (including positive thinking and negative thinking) and collaborative dispositions. Three self-rating instruments were employed to survey 901 college students' experience as research data. A series of analyses on the reliability and validity of instruments were conducted to validate the measurement model. The SEM analysis results indicated the structural model and the influences of both thinking styles on the youngsters' collaborative dispositions. In addition, it was concluded that only the individuals highly evaluating others were willing to and able to collaborate with others well. On the other hand, the factor of maladjustment and little desire for change was the dominant negative thinking which severely eliminated collaborative dispositions. Several suggestions were accordingly provided on the bases of research conclusions.