ERIC Number: EJ1026192
Record Type: Journal
Publication Date: 2013-Oct
Abstractor: As Provided
Reference Count: 10
Commentary: Gene by Environment Interplay and Psychopathology--In Search of a Paradigm
Nigg, Joel T.
Journal of Child Psychology and Psychiatry, v54 n10 p1150-1152 Oct 2013
The articles in this Special Issue (SI) extend research on G×E in multiple ways, showing the growing importance of specifying kinds of G×E models (e.g., bioecological, susceptibility, stress-diathesis), incorporation of sophisticated ways of measuring types of G×E correlations (rGE), checking effects of statistical artifact, exemplifying an impressive range of quantitative and biological methodologies, and pointing to clearly needed next-step studies such as summarizing across many genes in gene sets ("Bentley" et al. or in genome-wide pathway based approaches to G×E ("Winham & Biernacka") and prediction of clinical outcomes ("Rapee" et al.). As a group, they document nicely that gene × environment research has come of age. What is the import of this? Does it represent a major new development in our field, or merely an incremental change of a framework that remains fundamentally unchanged?
Descriptors: Genetics, Psychopathology, Correlation, Measurement Techniques, Clinical Diagnosis, Biology, Research Methodology, Statistical Analysis, Outcomes of Treatment, Therapy, Scientific Research
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Publication Type: Journal Articles; Reports - Descriptive
Education Level: N/A
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