Objective: The purpose of the present study was to evaluate the treatment effects of a relationship skills and family strengthening intervention for n = 726 high-risk, disadvantaged new parents. Method: Hierarchical linear modeling and regression models were used to assess intervention treatment effects. These findings were subsequently verified through two sensitivity analyses using propensity score analysis and growth curve modeling. Results: Analyses indicated 6 of 10 beneficial treatment effects were statistically significant, including relationship satisfaction, relationship quality, communication, conflict resolution, arguing, and emotional abuse. Most of these effects were verified in the more rigorous sensitivity analyses. Conclusion: Study findings suggest that this intervention is effective in helping disadvantaged couples improve relationship skills and strengthen family bonds.