Problem: College life brings with it many challenges for students' well-being including stress, trouble sleeping, anxiety, and difficulties with relationships. However, evidence of substantial variation in organization and availability of health-focused resources on college campuses has been documented and students' interest in health-related topics has not been thoroughly assessed. The objective of the study was to assess college students' interest in receiving health information by sex, age, relationship status, and living situation. Method: The sample included 238 college students (18 to 24 years) from a small Midwestern college. Results: Majority of students indicated interest in information about helping others in distress, sleep difficulties, and stress reduction. Females and younger students were more interested than males and older students in receiving information about stress reduction and helping others in distress. Relationship status and living situation were also associated with interest in receiving information. Conclusions: Exploratory findings indicate college students' interests in health topics differ and should be considered when planning health promotions.