In this article, the author describes a Seattle-based nonprofit organization, Powerful Voices, designed to help girls realize their dreams, engage their communities, and shape a better world. One among many efforts to address the equity gap for girls of color, Powerful Voices intertwines gender- and race-specific practices with evidence-based youth development practices. Using a skills- and strengths-based approach, it combines group meetings and one-on-one mentoring to build trust, communication skills, and goal-setting while exploring the roots of societal injustice through media literacy and anti-racism curricula. Girls use their newly acquired activism skills to develop a culminating project that champions a meaningful issue and fosters positive girl culture. Powerful Voices integrates best practices in girl-specific programming with those of the broader youth development field. Program evaluation results suggest that integrating the two approaches is a winning strategy for promoting academic gains among low-income girls of color. Herein, the author provides "what-you-can-do-now" suggestions for girl-specific programs that reflect current understanding. Youth development practice models and a hierarchy of program characteristics created by the Youth Program Quality Assessment (YPQA)--a quality improvement initiative launched by the Seattle-based Raikes Foundation--are described. The article concludes with implications and recommendations for youth development professionals and youth development programs.