Check-in/check-out (CICO) is a resource-efficient, mentor-based, Tier 2 intervention. Various problem behaviors of students with and without disabilities across traditional and alternative school settings have been impacted positively by CICO. Not all students respond to the traditional, five-step approach, however. This article provides an overview of three resource-efficient adaptations educators may consider prior to designing resource-intensive, Tier 3 (i.e., individualized) interventions for students who do not respond to traditional check-in/check-out.