As the choices that information technologies offer has increased, efficiency of these at education, the area and time it covers increases, as well. E-portfolio and social networks are the latest choices that informational technologies offer. In this study, both technologies have been used at education and results have been analyzed. For that purpose, there has been integrated an e-portfolio application prepared by the researcher on Facebook, which is one of the most popular social networks of the present-day and has been made available the use of for students. The study in which there has been used Isman Instructional Design Model has been used was carried out with 10th grade students studying at Tekirdag Technical and Industrial Vocational High School in the 2nd term of 2010-2011 academic year and it lasted for 18 weeks. Personal Information Questionnaire, Academic Success Test and Attitude Scale towards E-Portfolio Process have been used as data collection tools. It's observed that the averages of doing homework given for education and level of interest towards this homework have been fairly low, the interest of students towards the homework on e-portfolio application has been found as high. It has shown that e-portfolio application is a process in which students revel in participating. Although students have been abstained at the beginning of the application, creating original products, developing the skills of using technologies and having low grade anxiety has caused change of students' viewpoints towards the application positively. SPSS 17.0 packaged software has been used for the statistical analysis while evaluating the data obtained from the research. (Contains 5 figures and 3 tables.)