This paper examines the current stage of development of blended learning in higher education in China, South Korea and Japan, with a comparison to the city state of Singapore. It is noted that blended learning and e-learning are introduced at institutes of higher learning in these countries with varying degrees of success. A review of existing literature showed that there are a host of key issues and challenges which hampers higher education institutes in Asia from harnessing the full potential of blended learning. In China, for example, while blended learning was well-received, the dominance of traditional teaching methods goes against the conditions required for mainstreaming e-Learning. (Contains 2 tables and 1 footnote.)