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ERIC Number: EJ1009848
Record Type: Journal
Publication Date: 2013
Pages: 10
Abstractor: As Provided
Reference Count: 19
ISSN: ISSN-1470-8175
Using Microbial Genome Annotation as a Foundation for Collaborative Student Research
Reed, Kelynne E.; Richardson, John M.
Biochemistry and Molecular Biology Education, v41 n1 p34-43 Jan-Feb 2013
We used the Integrated Microbial Genomes Annotation Collaboration Toolkit as a framework to incorporate microbial genomics research into a microbiology and biochemistry course in a way that promoted student learning of bioinformatics and research skills and emphasized teamwork and collaboration as evidenced through multiple assessment mechanisms. Student teams in microbiology used bioinformatics tools to identify and characterize gene products from "Mucilaginibacter paludis" necessary for the synthesis of specific amino acids and then designed and carried out growth experiments to determine if the organism could indeed synthesize the amino acids. Students in biochemistry worked to characterize one of the amino acid biosynthetic pathways reconstructed by a previous microbiology class through amplification and cloning of the "M. paludis" genes and complementation analysis of "Escherichia coli" mutants. (Contains 7 figures and 1 table.)
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Publication Type: Journal Articles; Reports - Research
Education Level: Higher Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A