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ERIC Number: EJ1003237
Record Type: Journal
Publication Date: 2012-Dec
Pages: 4
Abstractor: As Provided
Reference Count: 15
ISSN: ISSN-0021-9584
NMR Studies of Structure-Reactivity Relationships in Carbonyl Reduction: A Collaborative Advanced Laboratory Experiment
Marincean, Simona; Smith, Sheila R.; Fritz, Michael; Lee, Byung Joo; Rizk, Zeinab
Journal of Chemical Education, v89 n12 p1591-1594 Dec 2012
An upper-division laboratory project has been developed as a collaborative investigation of a reaction routinely taught in organic chemistry courses: the reduction of carbonyl compounds by borohydride reagents. Determination of several trends regarding structure-activity relationship was possible because each student contributed his or her results to an overall data set in a situation similar to a research environment. The students learned to use [superscript 1]H NMR techniques for in situ kinetic determinations and collaborated with classmates to develop a complete theory for structure-activity effects in the kinetics of this fundamental organic reaction. (Contains 1 table, 1 figure, and 1 scheme.)
Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A