The study focused on the experiences of general and special education teachers on what constitutes successful collaboration since there is little evidence existing on the phenomenon. For collaboration to be successful, it must go beyond having two teachers in a classroom delivering instructions. It entails deliberate practices enabling teachers to meet the needs of all students cohesively. The purpose of this qualitative exploratory case study was to gain insights into the experiences of five pairs of co-teachers who practice successful collaboration in an urban school district in New York. Using triangulation techniques to add robustness to the data collection process, the researcher journaled, observed, and interviewed the co-teachers through focus group discussion. The focus of the questions used in the focus group discussion and journaling was to glean the experiences of the teachers on what constitutes successful collaboration. The data was analyzed in MS Word to derive common themes and coded using data and concept driven strategies. The analysis of the data revealed that successful collaboration is hinged on common planning time, teachers training and teachers' attitude. Additionally, the teachers expressed that the role of school administrators in collaboration must be more purposeful. The findings of the study implied that co-teachers need the training to equip them to practice collaboration in the classroom. There are three recommendations for future research and practice. First, the researcher recommends similar studies for other urban school districts. Second, the researcher suggests that a mixed methods approach be utilized with a larger sample to make the study more robust and the findings applicable to a wider audience. Finally, the researcher recommends that future researchers conduct studies involving school administrators' role in the collaboration process. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com/en-US/products/dissertations/individuals.shtml.]