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ERIC Number: ED567536
Record Type: Non-Journal
Publication Date: 2006
Pages: 144
Abstractor: As Provided
Reference Count: N/A
ISBN: 978-1-3038-1856-1
The Corpus Callosum and Reading: An MRI Volumetric Study
Fine, Jodene Goldenring
ProQuest LLC, Ph.D. Dissertation, The University of Texas at Austin
Researchers have long been interested in the role of the corpus callosum in reading disorder, but existing studies have yielded inconsistent results. Some have found larger corpus callosa in those with reading disorder, others have found smaller corpus callosa, and some have found no differences in the corpus callosa of persons with and without reading disability. Some possible problems with past studies include failure to control for whole brain size, intelligence, gender, lateral dominance, and the presence of other syndromes such as Attention Deficit Hyperactivity Disorder. The current study is an examination of the corpus callosum in 68 readers nested in 24 families. Data were centered around the family mean so that the variance within families could be determined. Corpus callosum volumes were measured and controlled for whole brain volume, intelligence, and gender. A series of regressions were used to determine whether the volume of the corpus callosum significantly contributed to the variance in oral reading, phonological processing, and rapid naming. The midsagittal slice was segmented into fifths, and similar regressions were performed. A logistic regression was used to determine whether variation in corpus callosum volume could predict RD and no RD group membership. Finally, left and right volumes were compared and a correlation between corpus callosum volume and area at the midsagittal slice were conducted. Results suggest that better readers within families have larger corpus callosum areas in the midsagittal slice at the midbody. Better phonological processors within families had smaller corpus callosum volumes, but a problem with restricted range for phonological processing scores renders this finding unreliable. Rapid naming scores appear to be unrelated to the corpus callosum in this sample. Differences in the corpus callosum are not robust enough to predict diagnostic group and there appears to be no differences between left and right hemisphere volumes of the corpus callosum. Measurements of area at the midsagittal slice are highly correlated with the volumetric measurements suggesting that for subsequent studies, area at the midsagittal slice may be sufficient. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page:]
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Publication Type: Dissertations/Theses - Doctoral Dissertations
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A