This study is a validity study of the recently revised version of the Health Science Standards. The purpose of this study is to understand how the Health Science Standards relate to college and career readiness, as represented by survey ratings submitted by entry-level college instructors of health science courses and industry representatives. For recruitment, WestEd researchers, with support from the Educational Policy Improvement Center (EPIC), contacted community colleges and health sector-related organizations throughout California. The survey was completed by 112 respondents, including 101 course instructors and 11 industry representatives. In conclusion, no standard was found to be not applicable by every respondent. Overall, every standard was rated as applicable to their course or occupational area by at least 21 (or almost 20%) of the survey respondents. Taken as a whole, the results from this study indicate a majority of respondents concur that the Career and Technical Education (CTE) Health Sciences and Medical Technology standards reflect adequate rigor (as measured by cognitive demand) and coverage necessary for students to be prepared for entry-level college nursing and biology courses. Appended are: (1) Standards Used in the Validity Study; (2) Course and Job Titles; (3) Individual Applicability and Importance Ratings; (4) Additional Questions; and (5) Open-Ended Responses to Additional Questions. (Contains 10 figures and 19 tables.)