With the downturn in growth of the U.S. economy and significant layoffs in the IT industry in 2009, retaining information technology (IT) workers is increasingly important to businesses as IT workers carry broad responsibilities for the analysis, design, implementation, and maintenance of critical business systems. Turnover of IT workers causes a significant, negative economic impact on an organization when considering the knowledge taken by the exiting employees. The current study involved examining the degree to which spirituality and job retention are related among IT workers. The relationship was examined through the combined use of the Spirituality Assessment Scale and Michigan Organizational Assessment Questionnaire. The combined use of these tools provided a quantitative, correlational approach. Members from the Association of Information Technology Professionals from organizations in the state of Missouri were asked to participate in the research. Using computations from the Pearson correlation coefficient for determinants of spirituality and the retention of IT workers, the obtained correlations used to test the relationship between the two were not statistically significant. There is not a strong predictive model for determinants of spirituality and the retention of IT workers. Leaders can surmise that even if employees have significant measures of spirituality, the employees will not necessarily have resultant low turnover intention outcomes. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com/en-US/products/dissertations/individuals.shtml.]