The use of Student Information Systems (SIS) to enhance school administration and manage student performance in K-12 education has received increased attention in recent years. As SIS become more integrated operational tools in schools, many school districts have to make decisions about the extent to which SIS affects student achievement and about the most appropriate SIS to adopt. Although many school districts are implementing Student Information Systems (SIS), there is little empirical evidence about whether SIS use can improve student performance. This article seeks to contribute to explicit understanding of the effectiveness of SIS within the context of K-12 education. It examines the effectiveness of one specific SIS--NCWISE--used in several hundreds of schools in the state of North Carolina in the United States. Questionnaire is appended. (Contains 4 tables and 1 figure.)