The purpose of this study was to empirically examine distance education learning outcomes and to determine if there was a statistically significant difference (p less than = 0.05) in grades between site-based students at selected locations and campus-based students who were enrolled in common courses offered at both locations during Fall Term 2004. This study was based on analyses of a Fall Term 2004 grades dataset that was provided to Nova Southeastern University's Office of Research, Planning, and Governmental Affairs by programming staff in the University's Office of Information Technologies and Digital Media. The findings from this study provide strong evidence that for undergraduate-level and graduate-level students, there is a general level of parity in the grades earned by site-based distance education students and their campus-based counterparts. Overall, for students at these two degree levels, distance education students did as well as campus-based students. The same finding can not be made, however, for the two sites that offered instruction to professional-level students. For these two sites, professional-level students had grades that did not meet the level of grades earned by campus-based students. However, it should be reminded that this study compared campus-based to site-based professional-level grades at only two sites. Further, at one site the difference, although statistically significant, raised the issue of practical significance. (Contains 4 footnotes, 21 tables, 9 figures.)