ERIC Number: ED471450
Record Type: Non-Journal
Publication Date: 2002-Aug
Reference Count: N/A
Importance of Depression in Diabetes.
Lustman, Patrick J.; Clouse, Ray E.; Anderson, Ryan J.
Depression doubles the likelihood of comorbid depression, which presents as major depression in 11% and subsyndromal depression in 31% of patients with the medical illness. The course of depression is chronic, and afflicted patients suffer an average of one episode annually. Depression has unique importance in diabetes because of its association with poor glycemic control, treatment nonadherence, and increased risk for complications of the metabolic disorder. Linkage with coronary heart disease is particularly strong--an association established in prospective and cross-sectional studies and most pronounced in diabetic women. While the number of available controlled depression treatment trials in diabetic patients is small, both pharmacological and psychotherapeutic approaches appear effective. Relief of depression also produces clinically significant improvements in glycemic control. Extant diabetes complications and hyperglycemia diminish responsiveness to antidepressant treatment and increase the risk for recurrence of depression. These observations suggest that concurrent management of both diabetes and depression is needed to optimize outcomes from depression treatment. (Contains 43 references and 3 figures.) (Author)
Publication Type: Information Analyses
Education Level: N/A
Audience: Practitioners; Researchers
Authoring Institution: N/A