This guide to universal design in the classroom is divided into two sections. The first addresses the concept of universal design for learning (UDL); the second addresses the practical application of UDL in the classroom. Each chapter opens with a summary of key ideas and a graphic organizer that illustrates how the concepts fit together. The eight chapters address the following topics: (1) "Education in the Digital Age;" (2) "What Brain Research Tells Us about Learner Differences;" (3) "Why We Need Flexible Instructional Media;" (4) "What Is Universal Design for Learning?;" (5) "Using UDL To Set Clear Goals;" (6) "Using UDL To Support Every Student's Learning;" (7) "Using UDL To Accurately Assess Student Progress;" and (8) "Making Universal Design for Learning a Reality". An appendix offers four classroom templates to help teachers apply the UDL framework. The templates address: a class learning profile, curriculum barriers, UDL solutions, and creating systematic change. Each template includes an introduction and three parts: an example of how the template might be used, collected sample items to use in the blank template, and a framework for applying UDL. (Contains approximately 150 references.) (DB)