ERIC Number: ED406787
Record Type: Non-Journal
Publication Date: 1995
Reference Count: N/A
Fragile X Syndrome in Males: Diagnostic, Behavioral, and Educational Implications.
Bellinger, Diane; And Others
This paper reviews the research on fragile X syndrome, the second most common cause of mental retardation related to chromosomal anomaly. It notes that far more males than females are affected by the fragile X syndrome, which typically results in craniofacial changes, delays in growth and development, speech/language difficulties, and cognitive deficits including mental retardation or learning disabilities. Topics reviewed include: diagnostic methods (direct DNA analysis is now preferred to cytogenetic analysis or DNA linkage studies); inheritance patterns (which explain the predominance of males); physical and cognitive characteristics; medical conditions associated with the condition (seizure disorders, motor coordination deficits); behavioral characteristics (hyperactivity, gaze avoidance); and speech/language characteristics (perseveration, cluttering, and echolalia). Other topics discussed are a possible relationship between autism and fragile X syndrome, whether language problems characteristic of the syndrome are due to qualitative or quantitative differences in language development, and the common presence of hypersensitivity. Interventions reviewed are organized into medical (especially drug therapy), and educational, which include classroom modifications, training in self-management skills, curricular modifications, and sensory integration therapy. (Contains 35 references.) (DB)
Descriptors: Autism, Behavior Patterns, Clinical Diagnosis, DNA, Drug Therapy, Educational Needs, Failure to Thrive, Genetics, Heredity, Intervention, Language Acquisition, Language Impairments, Learning Disabilities, Males, Medical Services, Mental Retardation, Multiple Disabilities, Sensory Integration, Special Health Problems, Symptoms (Individual Disorders)
Publication Type: Information Analyses
Education Level: N/A
Authoring Institution: Lynchburg Coll., VA.