In the winter of 1989-1990, the Bureau of Applied Studies of the New York State Office of Alcoholism and Substance Abuse Services (OASAS) conducted a major survey of alcohol and other drug use among students in public and private schools throughout the state. In addition to students in grades 7 through 12, who historically constitute the survey sample, this study included students who were at particular risk for dropping out of school. Also surveyed was a sample of residents in Division for Youth (DFY) facilities. This report focuses on survey findings for those youth who can be considered to be at high risk of engaging in alcohol and substance use. Three sections of the report deal with specific segments of youth-at-risk surveyed in the study: (1) students attending school on the day of the survey who otherwise indicate high rates of absence; (2) students attending alternative high school programs in New York City; and (3) residents of DFY residential facilities. Each section describes the demographic characteristics, substance-use findings, associated behaviors and help-seeking preferences for each segment of youth. A concluding section addresses the subpopulation of youth-at-risk who have dropped out of school totally and who are not represented in the study. (RJM)