Alcohol, tobacco, and drug use prevention is a goal shared by many. Prevention strategies aim to both reduce specific problems resulting from substance abuse and promote healthy development. Past efforts at prevention have included a variety of approaches: (1) prohibition; (2) scare tactics; (3) presenting factual information; (4) affective education; (5) providing alternatives; (6) interdiction; (7) social influences curricula; and (8) environmental control. Independently, none of these strategies have been demonstrated as completely effective. Current prevention theory stresses community involvement, the use of multiple strategies and ongoing activities, and seeks to integrate prevention strategies into the community. Some promising prevention programs focus on strategies to reduce specific problems related to alcohol, tobacco, and other drug use and include such efforts as providing people with instruction in personal and social skills so as to resist pressures to use alcohol, tobacco, and other drugs. Other efforts encourage the healthy development of individuals and include broad health promotion strategies. Furthermore, community prevention project grants from the Office for Substance Abuse Prevention have provided many communities with an opportunity to encourage collaboration and coalition building so as to assess local needs through multiple and integrated strategies. (RJM)