Job stress in health care professionals who provide care to Acquired Immune Deficiency Syndrome (AIDS) patients has been a subject of interest to a number of health center and hospital physicians, administrators, and to some extent, behavioral scientists. In this study psychosocial correlates of burnout and depression in HIV counselors were investigated using the Maslach Burnout Inventory, the depression scale (D-Scale) of the Minnesota Multiphasic Personality Inventory (MMPI), Rotter's Internal/External Locus of Control Scale (I/E Scale) and several questionnaires containing demographic and psychological variables. The three subscales of Burnout (i.e. Emotional Exhaustion, Depersonalization, and Personal Achievement) and the D-Scale constituted the four dependent variables. Subjects (N=102) including 23 males and 79 females involved in Human Immunodeficiency Virus (HIV) counseling participated in this study. Subjects ranged in age from 21 to 71 years old. Univariate and multivariate analyses were employed to determine the contributing factors of Burnout and Depression amongst HIV counselors. Results suggested that both dispositional and environmental factors play a role in the experience of burnout and depression among HIV counselors. Prominent among the variables affecting both Emotional Exhaustion and Depersonalization was the impact of the working environment and job demands faced by HIV counselors. (ABL)