ERIC Number: ED318140
Record Type: RIE
Publication Date: 1989
Reference Count: N/A
Intellectual Characteristics of Diabetic Children at Diagnosis and One Year Later.
Rovet, Joanne F.; And Others
A longitudinal investigation of neurocognitive function was conducted on 63 newly diagnosed pediatric patients with insulin-dependent diabetes mellitus (IDDM) at onset of illness and 1-year post diagnosis. The results at diagnosis, when the children were ages 4 months to 12 years, revealed no differences compared to sibling controls, nor any specific impairment predating illness. No evidence of any acquired impairment was found following 1 year of diabetes, although children who developed IDDM before age 5 performed more poorly than those with later onset on spatial tasks, while those with later onset scored lower on verbal tasks. Episodes of asymptomatic and mild chronic hypoglycemia were positively correlated with improved outcome over time. There were no adverse effects of severe hypoglycemia. Ketonuria and hospitalizations were associated with lower performance intelligence quotients 1 year post diagnosis, as was diabetic ketoacidosis at onset. The results are discussed in terms of critical periods of sensitivity of the brain to diabetes and the need for longer follow-up of these children. Includes 53 references. (JDD)
Publication Type: Reports - Research
Education Level: N/A
Authoring Institution: Hospital for Sick Children, Toronto (Ontario).