This study was designed to determine the relationship between the black college student's attitude toward science, science self-concept, and other variables of occupational choice and the selection of an academic major. The combined effect of the variables of occupational choice on the selection of an academic major was also examined. Science and non-science majors (N=410) at Morgan State University, Maryland, participated in the study. The student responses to questionnaires were entered into multiple regression analysis; the instruments were as follows: (1) the Purdue Masters Attitude Scale, Form B; (2) Brookover's Science Self-Concept of Ability Scale, Form B; and (3) a questionnaire especially designed for this project (Salters, 1985). Six variables were identified as being significant and accounted for 42 percent of the variance. These variables included: (1) science self-concept; (2) presence of role model; (3) image of the field; (4) course counseling; (5) attitude toward science; and (6) high school science background. References are also provided. (ML)