This document presents witness testimonies and prepared statements from the Congressional hearing called to examine the severe health problems of infants whose mothers abused drugs, alcohol, or tobacco during their pregnancies, or who suffer from acquired immunodeficiency syndrome (AIDS). Opening statements are included from Congressmen George Miller and Dan Coats, and from Congresswoman Lindy Boggs. Witnesses include: (1) Elaine B. Arkin, the chairperson of the steering committee, Healthy Mothers, Healthy Babies Coalition; (2) Ira J. Chasnoff, assistant professor of pediatrics and psychiatry at Northwestern University Medical School; (3) Sterling K. Clarren, associate professor of pediatrics, University of Washington School of Medicine; (4) Jennifer Custis, a parent; (5) Lawrence Fenton, professor of pediatrics, University of South Dakota School of Medicine; (6) James S. Marks, assistant director for science, Center for Health Promotion and Education, Centers for Disease Control; (7) James Oleske, director, division of allergy, immunology and infectious disease, University of Medicine and Dentistry of New Jersey; (8) Joyce N. Thomas, director, division of child protection, Children's Hospital National Medical Center; and (9) Benjamin Walker, Jr., chief executive officer, Odyssey Foundation of New York, Inc. Letters and supplemental materials appear throughout the text. (NB)