Strategic decision-making literature is reviewed, and applications to colleges and universities are made. The key requirement for strategic decision-making is that decisions affect the entire organization. While strategic decision-making can occur at different levels within the organization, the specific strategic decisions available to the planner at each level will vary depending on the issue addressed. Strategic decisions at colleges include: mission, program offerings, student clientele, geographic scope of activities, faculty-resource mix, and comparative advantage sought. In order for a unified organizational strategic thrust to occur, these strategic decisions need to be integrated. The achievement of this outcome can be illustrated by summarizing William Rothschild's categorization of types of generic strategy, with attention to strategies concerning investment, management, and implementation. It is noted that strategic decision-making assumes change is inevitable and focuses on preparing for change. An analogy is made between strategic decision-making and vector mathematics and also to sailboat racing to help illustrate the process. A three-page list of references concludes the document. (SW)