The 35th Annual Report of the National Science Foundation (NSF) describes recent achievements of NSF sponsored research in viral structure, semiconductors, genetic engineering, Mayan culture, astronomy, physiology, paleontology, robotics, physics, material science and pollution. Major 1985 initiatives included: (1) establishing six university Engineering Research Centers; (2) four Supercomputer Centers; (3) College Science Instrumentation Program; (4) Precollege Science Education Programs; (5) National Science Week; (6) Presidential Young Investigator Awards; (7) Interagency Arctic Research Policy Committee; (8) Office of Biotechnology Coordination; (9) increased mathematics support by 15 percent; and (1) procedures for reporting on science in other countries. Reviewed are several examples of cutting-edge research and educational activities, including special interdisciplinary research and educational communities. The report includes awards, notes senior staff appointments, presents organizational changes, provides policy notes and lists senior foundation and board officials. Future directions for support of research are explored. Appendixes include: (1) National Science Board Members and NSF staff; (2) financial report for fiscal year 1985; (3) patents and inventions resulting from NSF supported activities; and (4) Advisory Committee for fiscal year 1985. (JM)