A survey of 857 students at a large midwestern university provided information regarding the frequency and type of drugs used by students at any time and shortly before driving. The drugs most frequently used at least once in the prior year were alcohol, marijauna, caffeine, and nicotine. Significant association was found between alcohol use shortly before or while driving and the variables of moving violations, accidents, age, sex, driving experience in years and class rank. Significant association was also found between driving under the effects of marijauna and variables of sex, number of miles driven per year, frequency of driving, accidents and moving violations, as well as between alcohol use and marijuana use shortly before or while driving. Narcotic use as well as LSD, chemical vapors, cocaine and barbituates did not appear to be major factors in regard to substance use shortly before or while driving by college students in this study. It is suggested that educational programs should emphasize the effects of drugs on driving ability. Several tables provide statistical analyses of the data. (JD)