A two-quarter Human Anatomy and Physiology course for health-science students has been developed which incorporates the principles of individualization while maintaining the lecture hall setting. The lecture method contributes the following components to the course: (1) no special equipment or supplies; (2) personal interaction between instructor and students; (3) opportunity for easy revision and up-dating of materials; and (4) students meeting at one time. To individualize, components of personalized system of instruction (PSI) and audio-tutorial (AT) instruction have also been incorporated. Benefits of PSI include printed study guides and quizzing over each unit with immediate feedback. Benefits of AT include slide-tape minicourses (over each topic) available in a learning center, taped lectures so students can listen at their own pace, and use of several types of media to support the lectures. Overall benefits of this individualized lecture course (ILC) include personal interaction between students and teachers, use of slide-tapes in the media center, refinement of note-taking skills, feedback from classroom questions and tests, and use of study guides that direct study efforts to more important areas and resource materials. Student response to the course is reported to be favorable. (Author/JN)