This paper contains the revised drug education guidelines for the state of California, which emphasize prevention of alcohol and drug abuse. The materials define school-based alcohol and drug abuse prevention programming as a comprehensive process that not only provides students with accurate information about alcohol and drugs, but also enhances self-esteem, communication skills, decision-making skills, and interpersonal relationships. The guidelines include: (1) a series of recommendations to administrators; (2) a general philosophy of and approach to school-based prevention; and (3) examples of effective programs dealing with drug and alcohol information, affective behavior, peer and family relationships, and life/career planning. Suggestions for implementing a comprehensive school-based prevention program focus on curriculum design, inservice training, staffing, counseling, and parent and community involvement. Relevant sections of the California Education code are cited, along with a list of resources and services. (NRB)