Published November 4, 1975 in the Federal Register, these Regulations have been developed by the Bureau of Indian Affairs (BIA) to assist American Indians in implementation of the Indian Self-Determination and Education Assistance Act (PL 93-368). Prepared for tribal leaders and policymakers, this handbook analyzes the Regulations from the perspective of tribal policymakers, presents options as provided by the Regulations for creative tribal programming and development, and provides specific examples of how the Regulations' tools (self-determination grants, BIA program contracts, planning for BIA operated programs, and gaining access to Federal personnel) can best be used to help tribes solve problems and achieve goals. Divided into three major sections, this handbook includes the following: (1) Key Principles of the Self-Determination Act and Regulations; (2) Analysis of the Title I Self-Determination Regulations (grants, contracting, tribal planning for BIA operated programs, and personnel tools under the Act); (3) Options and Considerations in Using the Tools of the Self-Determination Regulations (grants program options and tools, considerations in deciding whether to contract, consideration in securing personnel for contracted programs, integrating self-determination tools, and flow chart for contracting actions). (JC)