Children's successful adjustment to child care involves effectively managing their separation from parents. Persistent problems with separation interfere with other relationships and with learning opportunities. The authors of this article developed a tool that caregivers can use to identify adjustment difficulties in young children who are entering or transitioning in child care settings, and create a plan for intervention. The authors provide a detailed description of each component of the E-CARE instrument and provide specific guidance for its implementation. The authors also share their vision of professional development, emphasizing that child care providers must come to see prevention, early identification, and intervention as crucial components of their role as caregiving professionals.